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Product Reviews. Health Articles. Special Offers. My Cart. Enable JavaScript support in your browser and reload this page. Disposable Diapers Infant Care by Dr. Huggies, Pampers, Luvs, Honest by Dr. Latest Articles. Top Selling Brands. Health Advice. Your path to wellness. Safety The U. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.

Consult a healthcare provider immediately if you experience side effects. Allergies Avoid in individuals with a known allergy or hypersensitivity to Tribulus terrestris or its constituents. Side Effects and Warnings Tribulus terrestris appears to be generally safe with a few adverse events of insomnia and menorrhagia heavy menstrual bleeding occurring. Use cautiously in patients with menstrual disorders. One case of pneumothorax air between the lungs and the lining of the chest cavity upon digestion of the fruit has been reported.

In another case report, the patient developed a polyp in the lobar bronchus of the right interior lobe due to the presence a tribulus fruit spine. In a case report, gynecomastia excessive development of male breasts was observed in a weight-trainer taking an herbal supplement containing tribulus. However, these adverse effects cannot be solely attributed to tribulus, due to the other ingredients in this product. Although not well studied in humans, a saponin from tribulus may reduce levels of glucose and total cholesterol. Use cautiously in patients with diabetes high blood sugar or using hypoglycemic blood sugar altering medication, as tribulus may decrease blood sugar levels.

Although not well studied in humans, tribulus may increase prostate weight.

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Use cautiously in patients with benign prostatic hyperplasia enlarged prostate or prostate cancer. Pregnancy and Breastfeeding Tribulus is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence. Traditionally, tribulus has been used as an abortifacient induces abortion. Interactions Interactions with Drugs Tribulus may add to calcium channel blocker or beta-blocker effects due to its negative chronotropic activity in cardiac muscle. Tribulus may exacerbate digoxin effects. Caution is advised. Tribulus may exhibit diuretic effects increases urine flow.

Caution is advised when used with other drugs that have diuretic effects. Tribulus may lower blood glucose levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary. Tribulus has been found to have blood pressure lowering effects, and may affect patients taking drugs that also alter blood pressure. Based on preliminary study and studies of combination products containing tribulus , tribulus may increase levels of steroid hormones.

Interactions with Herbs and Dietary Supplements Tribulus may exacerbate the effects of cardiac glycoside herbs.

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Tribulus may exhibit diuretic effects increase urine flow. Caution is advised when used with other herbs that have diuretic effects. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment. Tribulus has been found to have blood pressure lowering effects, and may affect patients taking herbs that also alter blood pressure. Attribution This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration www.

Biologically active steroidal glycosides from Tribulus terrestris.

Pharmazie ;57 7: Effects of androstenedione-herbal supplementation on serum sex hormone concentrations in to year-old men. Int J Vitam. Res ;71 5: A novel furostanol saponin from Tribulus terrestris of Bulgarian origin. Fitoterapia ;75 2: Furostanol saponins from Tribulus terrestris. Fitoterapia ;74 6: Tribulosin and beta-sitosterol-D-glucoside, the anthelmintic principles of Tribulus terrestris.

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Di Yi. Aphrodisiac properties of Tribulus Terrestris extract Protodioscin in normal and castrated rats. Life Sci ;71 Terrestrinins A and B, two new steroid saponins from Tribulus terrestris. J Asian Nat Prod Res ;5 4: Gynaecomastia and the plant product "Tribulis terrestris". Breast ;13 5: